Total synthesis of (+)-phrymarolin I from (+)-malic acid

Article abstract of DOI:10.1271/bbb.61.660

(+)-Phrymarolin I was stereoselectively synthesized from (R)-(+)-3-hydroxybutanolide that had been prepared from (+)-malic acid. The procedure is more efficient than our previous synthesis in terms of fewer reaction steps and the easier availability of the starting material.

Full text of DOI:10.1271/bbb.61.660

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Bioscience, Biotechnology, and Biochemistry
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Total Synthesis of (+)-Phrymarolin I from (+)-Malic
Acid
Momotoshi Okazakia, Fumito Ishibashiab, Yoshihiro Shutoa & Eiji Taniguchiac
a Faculty of Agriculture, Ehime University, Matsuyama 790, Japan
b Faculty of Fisheries, Nagasaki University, Nagasaki 852, Japan
c Faculty of Agriculture, Kyushu University, Fukuoka 812, Japan
Published online: 12 Jun 2014.
To cite this article: Momotoshi Okazaki, Fumito Ishibashi, Yoshihiro Shuto & Eiji Taniguchi (1997) Total Synthesis of (+)-
Phrymarolin I from (+)-Malic Acid, Bioscience, Biotechnology, and Biochemistry, 61:4, 660-663, DOI: 10.1271/bbb.61.660
To link to this article: http://dx.doi.org/10.1271/bbb.61.660
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