Tetrahedron Letters p. 3189 - 3192 (1997)
Update date:2022-07-30
Topics:
Evans, David A.
Dinsmore, Christopher J.
Ratz, Andrew M.
The course of the Tl(III)-mediated intramolecular oxidative macrocyclization of phenolic residues to provide the M(2-4) diarylether ring of the vancomycin antibiotics is remarkably sensitive to transannular effects across the M(4-6) ring, brought about by variations in the degree of ring-6 chlorination as well as the conformational bias imparted by the distal M(5-7) ring. The effect of structure on this reaction is documented.
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Doi:10.1002/jhet.5570340233
(1997)Doi:10.1021/jo962416u
(1997)Doi:10.1016/S0277-5387(96)00538-4
(1997)Doi:10.1016/S0022-1139(96)03551-8
(1997)Doi:10.1016/S0040-4039(97)00681-3
(1997)Doi:10.1016/j.tetlet.2011.03.070
(2011)
