Highly cis-selective Horner-Wadsworth-Emmons (HWE) reaction of methyl bis(2,4-difluorophenyl) phosphonoacetate

Article abstract of DOI:10.1080/00397919708004100

Of the previously reported Homer-Wadsworth-Emmons (HWE) reaction, the olefination of methyl bis(2,4-difluorophenyl)phosphonoacetate (1a) with various aldehydes gave unsaturated esters in the highest cis-selectivity.

Full text of DOI:10.1080/00397919708004100

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Highly Cis-Selective Horner-
Wadsworth-Emmons
(HWE) Reaction of Methyl
Bis(2,4-Difluorophenyl)
Phosphonoacetate
Keisuke Kokin a , Jiro Motoyoshiya a , Sadao Hayashi
a & Hiromu Aoyama a
a Department of Chemistry, Faculty of Textile
Science & Technology , Shinshu University , Ueda,
Nagano, 386, Japan
Published online: 21 Aug 2006.
To cite this article: Keisuke Kokin , Jiro Motoyoshiya , Sadao Hayashi & Hiromu
Aoyama (1997) Highly Cis-Selective Horner-Wadsworth-Emmons (HWE) Reaction of
Methyl Bis(2,4-Difluorophenyl) Phosphonoacetate, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 27:14,
2387-2392, DOI: 10.1080/00397919708004100
To link to this article: http://dx.doi.org/10.1080/00397919708004100
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