Heterocycles p. 723 - 734 (1997)
Update date:2022-08-03
Topics:
El-Ahmad, Youssef
Maillet, Philippe
Laurent, Elisabeth
Talab, Akram
Tran, Gilles
Ollivier, Roland
A series of 1-[co-[(arylamino)carbonyl]alkyl]-4-(benzocycloalkyl)-piperazines (1a-v) was prepared either by reacting the precursor 4-[ω-[(arylamino)carbonyl]alkyl]piperazine (2a-j) with 1-chlorobenzocycloalkanes (3a-c) (Procedure A) or by reacting the N-aryl-ω-chloroalkanamides (5a-j) with the 4-(benzocycloalkyl)piperazines (10a-c) (Procedure B). The best yields were obtained using procedure A.
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Doi:10.1016/S0960-894X(00)00717-4
(2001)Doi:10.1002/chem.19970030518
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(1997)
