Tetrahedron p. 6555 - 6564 (1997)
Update date:2022-08-04
Topics:
Miguel del Corral, Jose M.
Gordaliza, Marina
Castro, M. Angeles
Lopez-Vazquez, M. Luisa
Garcia-Gravalos, M. Dolores
Broughton, Howard B.
San Feliciano, Arturo
A new type of cyclolignans with an isoxazoline ring fused to the cyclolignan core has been prepared from 7-ketolignanolides by reaction with hydroxylamine. The corresponding 7-oxime derivatives have also been obtained. The compounds prepared have been evaluated for their cytotoxic activities over four cell lines.
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Doi:10.1078/0171-2985-00128
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