Tetrahedron Letters p. 4277 - 4280 (1997)
Update date:2022-08-03
Topics:
Serelis, Algirdas K.
Simpson, Gregory W.
Esters of chiral auxiliaries with α-(4-ethoxyphenyl)acrylic acid undergo diastereoselective addition reactions with tetrafluoroethylene at 130°- 170°to afford tetrafluorocyclobutanecarboxylic esters. The oxazoline derived from (+)-(1S,2R)norephedrine and α-(4-ethoxyphenyl)acrylic acid shows negligible stereoselectivity.
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