Bioorganic and Medicinal Chemistry Letters p. 1833 - 1836 (1997)
Update date:2022-07-29
Topics:
Sodeoka, Mikiko
Baba, Yoshiyasu
Kobayashi, Satoko
Hirukawa, Nozomu
The effects of structural modification of cantharidin on the inhibition of protein Ser/Thr phosphatases are described. Removal of the methyl substituents at C2 and C3 in cantharidin improved the inhibition of PP2B. In contrast, introduction of a substituent to C1/C4-position drastically decreased inhibition of PP1 and PP2A1. PP2B was found to be quite tolerant to modifications at the C5 position.
View MoreChongqing Yawei Fine Chemical Co.,Ltd
Contact:0086-23-62849407
Address:Ziyou village, Nanquan town, Banan district, Chongqing China
Contact:+86 18616952870
Address:Area
Purestar Chem Enterprise Co.,Ltd
website:http://www.purestarchem.com
Contact:05722157374
Address:no235.huanchengdong Rd
Hunan Shineway Enterprise Co., Ltd.
Contact:+86-731-86303875
Address:118, Huanghua International Airport Road, Huanghua Town, Changsha, Hunan 410137, China
Contact:86-791-86629460
Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
Doi:10.1016/j.tet.2015.03.028
(2015)Doi:10.1021/jo200466t
(2011)Doi:10.1002/ejoc.201900947
(2019)Doi:10.1002/anie.201008153
(2011)Doi:10.1016/0022-328X(90)87277-K
(1990)Doi:10.1016/j.tetlet.2011.03.102
(2011)
