
Bioorganic and Medicinal Chemistry Letters p. 199 - 200 (1998)
Update date:2022-08-02
Topics:
Tamiz, Amir P.
Whittemore, Edward R.
Schelkun, Robert M.
Yuen, Po-Wai
Woodward, Richard M.
Cai, Sui-Xiong
Weber, Eckard
Keana, John F. W.
A series of N-(2-phenethyl)cinnamides was synthesized and assayed for antagonism at three N-methyl-D-asparate (NMDA) receptor subtypes (NR1A/2A-C). N-(2-(4-hydroxyphenyl)ethyl)-4-chlorocinnamide (6) was identified as a highly potent and selective antagoni
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