N-(2-(4-hydroxyphenyl)ethyl)-4-chlorocinnamide: A novel antagonist at the 1A/2B NMDA receptor subtype

DOI: 10.1016/S0960-894X(97)10215-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 199 - 200 (1998)

Update date:2022-08-02

Topics:

Authors:

Tamiz, Amir P.

Whittemore, Edward R.

Schelkun, Robert M.

Yuen, Po-Wai

Woodward, Richard M.

Cai, Sui-Xiong

Weber, Eckard

Keana, John F. W.

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Article abstract of DOI:10.1016/S0960-894X(97)10215-3

A series of N-(2-phenethyl)cinnamides was synthesized and assayed for antagonism at three N-methyl-D-asparate (NMDA) receptor subtypes (NR1A/2A-C). N-(2-(4-hydroxyphenyl)ethyl)-4-chlorocinnamide (6) was identified as a highly potent and selective antagoni

Full text of DOI:10.1016/S0960-894X(97)10215-3

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Product name:2-Propenamide, 3-(4-chlorophenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (E)-

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