Palladium catalysed tetramolecular cascade processes incorporating allene and carbon monoxide

Article abstract of DOI:10.1016/S0040-4039(97)01062-9

Chemo- and regio-specific palladium catalysed four component cascade processes, involving formation of 4 new bonds, initiated by oxidative addition of Pd(0) with aryl/heteroaryl iodides followed by sequential incorporation of CO(latm), allene (latrn) and an S- or N-nucleophile[PhSO₂- or (RNTs)^-] occur in good to excellent yield at 50°C.