Reductive diallylation of natural amino acids with triallylborane. The first synthesis of chiral 1,1-diallyl-2-amino alcohols and their cyclization into optically active pyrrolidines

DOI: 10.1016/S0040-4039(97)01402-0

Source and publish data:

Tetrahedron Letters p. 6259 - 6262 (1997)

Update date:2022-08-03

Topics:

Authors:

Bubnov, Yuri N.

Misharin, Mikhail A.

Ignatenko, Anatoly V.

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Article abstract of DOI:10.1016/S0040-4039(97)01402-0

The titled amino alcohols are obtained by treatment of chiral amino acids with triallylborane. Electrophylic iodocyclization of the alcohols leads to pyrrolidine derivatives.

Full text of DOI:10.1016/S0040-4039(97)01402-0

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