The (2-cyano-1-phenyl)ethoxycarbonyl (cpeoc) group-a new protecting group for oligoribonucleotide synthesis

Article abstract of DOI:10.1080/07328319708002955

The (2- cyano-1-phenyl)ethoxycarbonyl (cpeoc) group was developed as a new base-labile protecting group for the 5-OH function in solid-phase synthesis of oligoribonucleotide by the phosphoramidite approach using the 4- methoxytetrahydropyran-4-yl (mthp) group for 2'-protection. The syntheses of the monomeric building blocks and the first oligoribonucleotides obtained by this approach are described.

Full text of DOI:10.1080/07328319708002955

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Nucleosides and Nucleotides
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The (2-Cyano-1-
phenyl)ethoxycarbonyl (CPEOC)
Group-A New Protecting Group for
Oligoribonucleotide Synthesis
Ursula Münch a & Wolfgang Pfleiderer a
a Fakultät für Chemie, Universiät Konstanz, Postfach 5560,
D-78434, Konstanz
Version of record first published: 22 Aug 2006.
To cite this article: Ursula Münch & Wolfgang Pfleiderer (1997): The (2-Cyano-1-
phenyl)ethoxycarbonyl (CPEOC) Group-A New Protecting Group for Oligoribonucleotide Synthesis,
Nucleosides and Nucleotides, 16:5-6, 801-808
To link to this article: http://dx.doi.org/10.1080/07328319708002955
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