Stereoselective sulfoxide directed reduction of 1,2-diketo-derivatives to enantiomerically pure syn and anti 1,2-diols

Article abstract of DOI:10.1016/S0040-4039(97)01300-2

A new route to enantiopure syn and anti 1,2-diols is described from oxalyl-di-(N-methyl-N-methoxyamide) via the corresponding β-ketosulfoxide. This is the first report of the stereoselective reduction of a γ-keto-β-hydroxysulfoxide.