Tetrahedron Letters p. 5989 - 5992 (1997)
Update date:2022-08-05
Topics:
Tellier, Frederique
Baudry, Monique
Sauvetre, Raymond
A new method for the synthesis of various 1,1-difluoroolefins is described. The key step is the treatment of 1-bromo-1,1-difluoro-2-alkenes with organo-metallic reagents in the presence of copper and lithium salts.
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Doi:10.1039/c1cc16417a
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