Stereoselective synthesis of 4-deoxy-4-nucleobase-2,5-anhydro-L-mannitol derivatives

Article abstract of DOI:10.1016/S0957-4166(97)00314-5

2,5:3,4-Dianhydro-L-talofuranose dimethylacetal 7 was synthesized from D-glucose in 7 steps. A series of 4-deoxy-4-nucleobase-2,5-anhydro-L-mannitols 13-16 were synthesized regioselectively from 7 in good yields. 6-O-p-Tolylsulfonyl-2,5:3,4-dianhydro-L-ta