Efficient generation and intramolecular cyclization reactions of acyl imines

DOI: 10.1016/S0040-4039(97)01531-1

Source and publish data:

Tetrahedron Letters p. 6545 - 6548 (1997)

Update date:2022-08-03

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Authors:

DeNinno, Michael P.

Eller, Cynthia

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Article abstract of DOI:10.1016/S0040-4039(97)01531-1

Acyl carbamates can be selectively reduced with diisobutyl aluminum hydride to provide high yields of N-acyl hemiaminals 1. With appropriate substitution, these intermediates undergo Lewis acid catalyzed intramolecular exo cyclization reactions to afford

Full text of DOI:10.1016/S0040-4039(97)01531-1

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