Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand

DOI: 10.1021/jm970402q

Source and publish data:

Journal of Medicinal Chemistry p. 3719 - 3725 (1997)

Update date:2022-08-03

Topics:

Authors:

Plummer, Mark S.

Holland, Debra R.

Shahripour, Aurash

Lunney, Elizabeth A.

Fergus, James H.

Marks, James S.

McConnell, Patrick

Thomas Mueller

Sawyer, Tomi K.

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Article abstract of DOI:10.1021/jm970402q

The specific association of an SH2 domain with a phosphotyrosine (pTyr)- containing sequence of another protein precipitates a cascade of intracellular molecular interactions (signals) which effect a wide range of intracellular processes. The nonreceptor

Full text of DOI:10.1021/jm970402q

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