Bioorganic and Medicinal Chemistry Letters p. 2657 - 2660 (1997)
Update date:2022-08-03
Topics:
Nishikawa, Asuka
Shirai, Ryuichi
Koiso, Yukiko
Hashimoto, Yuichi
Iwasaki, Shigeo
A series of side chain-modified analogs of curacin A, a powerful antimitotic agent isolated from a Caribbean cyanobacterium was synthesized and the effect of these compounds on in vitro microtubule polymerization was examined. The analogs showed weak or no anti-tubulin activity, suggesting that the whole side chain structure of curacin A is required for the interaction with tubulin.
View MoreHangzhou Sartort Biopharma Co., Ltd
website:http://www.sartort.com
Contact:86-571-87039693
Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China
Tianjin Chemsyntech Chemical Co., Ltd
Contact:+86-22-60872258
Address:Haitai green industry base in Tianjin, K1,5-601
jintan yufan Medicine Raw materials Co.,Ltd.(expird)
Contact:86-519-82808282
Address:6th,Jincheng Huangzhuang
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.
Contact:+86-(574)-81110986
Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Ji'an Hairui Natural Plant Co. Ltd.
Contact:0796-8105528
Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province
Doi:10.1021/js970133r
(1998)Doi:10.1021/jo00429a002
(1977)Doi:10.1021/jo01260a050
(1969)Doi:10.1111/j.2042-7158.1962.tb11132.x
(1962)Doi:10.1021/jm00125a003
(1989)Doi:10.1021/ja00035a050
(1992)