Direct N3 Alkylation of Uracil and Derivatives via N1-[2-(trimethylsilyl)ethoxymethyl] Protection

DOI: 10.1055/s-1997-1029

Source and publish data:

Synlett p. 1233 - 1234 (1997)

Update date:2022-08-03

Topics:

Authors:

Arias Arias

Guzmán Guzmán

Jaime-Figueroa

Lopez Lopez

Morgans Jr.

Padilla Padilla

Pérez-Medrano

Quintero

Romero Romero

Sandoval

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Article abstract of DOI:10.1055/s-1997-1029

Protection at N₁ position of uracil and uracil analogs as 2-(trimethylsilyl)ethoxymethyl derivatives permits the clean alkylation at N₃. These protected uracils are quite stable in a wide range of pH.

Full text of DOI:10.1055/s-1997-1029

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