Synthesis of 1'-(2-diarylphosphino)1-naphthyl)isoquinolines; variation of the aryl substituent

Article abstract of DOI:10.1016/S0957-4166(97)00556-9

A series of phosphinamines in which the aryl substituents are varied has been prepared from the known triflate 1 by palladium catalysed reaction with the appropriate secondary phosphine oxide followed by reduction with trichlorosilane. In four of the six