Highly enantioselective reduction of symmetrical diacetylaromatics with baker's yeast

DOI: 10.1016/S0957-4166(97)00462-X

Source and publish data:

Tetrahedron Asymmetry p. 3467 - 3474 (1997)

Update date:2022-09-26

Topics:

Authors:

Uchiyama, Masahiko

Katoh, Nobuo

Mimura, Rio

Yokota, Naoko

Shimogaichi, Yuki

Shimazaki, Makoto

Ohta, Akihiro

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Article abstract of DOI:10.1016/S0957-4166(97)00462-X

Asymmetric reduction of symmetrical diacetylaromatics (1a, 1b, and 1d- g) with baker's yeast (Saccharomyces cerevisiae) provided the corresponding alcohols of high enantiomeric purity. By choosing appropriate reaction conditions, the products were preferentially the monoalcohols over the diols.

Full text of DOI:10.1016/S0957-4166(97)00462-X

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