Complete diastereocontrol in [3+2] cycloaddition reactions: Synthesis of enantiomerically pure fluoromethyl substituted β-amino acids

Article abstract of DOI:10.1016/S0040-4020(97)10199-5

The intramolecular reaction of nitrones of crotonic and cinnamic esters of (S)-3-fluoro-2-hydroxypropanal afforded corresponding cycloadducts in good chemical yields and complete stereoselection.