Novel design of nonpeptide AVP V2 receptor agonists: Structural requirements for an agonist having 1-(4-aminobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine as a template

DOI: 10.1021/jm000108p

Source and publish data:

Journal of Medicinal Chemistry p. 4388 - 4397 (2000)

Update date:2022-08-04

Topics:

Authors:

Kondo Kondo

Ogawa Ogawa

Shinohara

Kurimura

Tanada Tanada

Kan Kan

Yamashita

Nakamura

Hirano Hirano

Yamamura

Mori Mori

Tominaga

Itai Itai

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm000108p

The discovery of a series of nonpeptide arginine vasopressin V₂ receptor agonists is described. After identifying the aniline derivative 8 as our lead compound from the metabolites of compound 7 that showed antidiuretic activity by po administr

Full text of DOI:10.1021/jm000108p

Products guided by the article

Product name:(2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)-2-chloro-4-nitrobenzamide

Cas No:200729-53-9

R&D Labs maybe for 200729-53-9

Jinan Jianfeng Chemical Co., Ltd

Contact:0086-531-88110457

Address:sales01(-a-t-)pharmachemm{dot}c+o+m
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Shanxi Tongji Pharmaceuticals Co., Ltd.

Contact:+86-359-3024784

Address:Xikuang South Road, Ruicheng County , Shanxi
HANGZHOU TOYOND BIOTECH CO., LTD

Contact:+86-571-86965177

Address:No. 189, Fengqi East Road, Hangzhou, China
Tradlon Chemical Co., Ltd.

Contact:+86-710-3516804

Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei

Relevant to this article

Preparation and reactions of Cp₂HfRCl, Cp₂HfRR′ and hafnacyclopent-2-enes

Doi:10.1016/S0022-328X(97)00375-6
(1997)
Heterogeneous Catalysis in Carbonyl Regeneration from 1,3-Dithiolanes and 1,3-Dithianes by Zirconium Sulfophenyl Phosphonate

Doi:10.1055/s-1997-5751
(1997)
Tripod-Liganden mit cyclopentadienyl-donorgruppe: Synthese und reaktivitaet von komplexen des typs CH₃C(CH₂-η⁵-C₅H₄)(CH₂PR₂)(CH₂pr′₂)FeCl

Doi:10.1016/S0022-328X(97)00502-0
(1997)
Synthesis and characterisation of thioether crown hydrazones, and palladium(II) and platinum(II) complexes of 6-(2,4-dinitrophenylhydrazono)-1,4,8,11-tetrathiacyclotetradecane

Doi:10.1039/a705996e
(1998)
Synthesis of Adenine Dinucleosides 2′,5′-Bridged by Sulfur-Containing Linkers as Bisubstrate SAM Analogues for Viral RNA 2′-O-Methyltransferases

Doi:10.1002/ejoc.201901120
(2019)
The oxidative addition of a vinylic C-H bond of divinyl(phenyl)phosphine at M₃(CO)₁₂ carbonyls (M = RU, Os). Stepwise formation and crystal structure of [(μ-H)RU₃(CO)₈{PPh(CH=Ch₂)₂}{μ₃-PPh(CH=CH₂) (CH=CH)}]

Doi:10.1016/S0022-328X(97)00272-6
(1997)

Article Doi