Synthesis p. 1489 - 1494 (1997)
Update date:2022-08-03
Topics:
Guan, Hui-Ping
Tang, Xiao-Qing
Luo, Bing-Hao
Hu, Chang-Ming
A convenient synthesis of fluoroalkyl-substituted heterocycles including 3-trifluoromethylpyrazoles 7,5-trifluoromethylisoxazoles 8 and 4-trifluoromethylpyrimidines 9 is described. This two-step sequence consists of a radical addition of fluoroalkyl iodid
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