Convenient synthesis of fluoroalkyl-substituted heterocycles from 1-fluoroalkyl-2-iodoalkenes

DOI: 10.1055/s-1997-1376

Source and publish data:

Synthesis p. 1489 - 1494 (1997)

Update date:2022-08-03

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Authors:

Guan, Hui-Ping

Tang, Xiao-Qing

Luo, Bing-Hao

Hu, Chang-Ming

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Article abstract of DOI:10.1055/s-1997-1376

A convenient synthesis of fluoroalkyl-substituted heterocycles including 3-trifluoromethylpyrazoles 7,5-trifluoromethylisoxazoles 8 and 4-trifluoromethylpyrimidines 9 is described. This two-step sequence consists of a radical addition of fluoroalkyl iodid

Full text of DOI:10.1055/s-1997-1376

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