GLUCOSYLATION OF PHENOLIC COMPOUNDS BY PLANT CELL CULTURES

Article abstract of DOI:10.1016/0031-9422(88)84097-4

Key Word Index-Glucosylation; biotransformation; plant cell culture; simple phenol;coumarin; flavonoid; anthraquinone.Ten culture strains derived from seven species of plants were examined for their ability to glucosylate exogenous phenolic compounds including four simple phenols, four coumarins, three flavonoids and three anthraquuinones.Suspension cultures of Datura, Lithospermum, Perilla and Catharanthus were capable of glucosylating m-hydroxybenzoic acid, umbelliferone, esculetin, daphnetin and liquiritigenin.In particular, Datura cultures glucosylated ca 90percent of umbelliferon within 24 hr after administration.Only Perilla cultures were capable of gucosylating rhein and emodin.The ability of glucosylating isomeric hydroxybenzoic acids varied widely with culture strains.A culture strain of Mallotus transformed p-hydroxybenzoic acid to p-O-β-D-glucosylbenzoic acid and p-hydroxybenzoic acid glucose ester, whereas only o-O-β-D-glucosylbenzoic acid was formed from o-hydroxybenzoic acid.