The 2-(acetoxymethyl)benzoyl (AMB) group as a new base-protecting group, designed for the protection of (phosphate) modified oligonucleotides

DOI: 10.1016/S0040-4039(00)97159-4

Source and publish data:

Tetrahedron Letters p. 6729 - 6732 (1990)

Update date:2022-07-29

Topics:

Authors:

Kuijpers

Huskens Huskens

Van Boeckel

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Article abstract of DOI:10.1016/S0040-4039(00)97159-4

The 2-(acetoxymethyl)benzoyl (AMB) group is a new base-protecting group that facilitates the synthesis of labile, modified nucleotides, since it can be rapidly cleaved under mild basic conditions.

Full text of DOI:10.1016/S0040-4039(00)97159-4

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