Reactivity of 2-Cyano-1,4,5,6-tetrahydro-1-pyridinecarboxylic Acid Esters Towards Various Nucleophiles: Regio- and Stereoselectivity of the Attack

Article abstract of DOI:10.1007/BF00806971

The synthesis and reactivity of the title compounds towards nucleophiles are discussed. The regio- and diastereoselectivity of the attack is highly dependent on the carbamic ester and the type of nucleophile applied. Both Michael type addition across the