New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method

DOI: 10.1016/S0040-4039(97)10677-3

Source and publish data:

Tetrahedron Letters p. 923 - 926 (1998)

Update date:2022-08-03

Topics:

Authors:

Ojima, Iwao

Wang, Hong

Wang, Tao

Ng, Edward W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)10677-3

New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.

Full text of DOI:10.1016/S0040-4039(97)10677-3

Products guided by the article

Product name:Acetic acid [(2S,3R)-1-(4-methoxy-phenyl)-4-oxo-3-triisopropylsilanyloxy-azetidin-2-yl]-phenyl-methyl ester

Cas No:203806-58-0

R&D Labs maybe for 203806-58-0

Hubei Lansun Biochemical Pharmaceutical Co., Ltd

Contact:714-6395977

Address:No. 81 Pengcheng Avenue, economic and technological development zone, Huangshi City, Hubei Province,China
Nantong Auxin Electronic Technology Co., LTD

Contact:86-513-88760026

Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
EnBridge PharmTech Co., Ltd.

website:http://www.enbridgepharm.com

Contact:+86-510-83591909

Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Ningbo Inno Pharmchem Co., Ltd.

Contact:86-574-87319282

Address:6F-5,NO.163 RUIQING RD.,NINGBO 315000 CHINA
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china

Relevant to this article

Aryl biphenyl-3-ylmethylpiperazines as 5-HT₇ receptor antagonists

Doi:10.1002/cmdc.201300240
(2013)
Dually acting nonclassical 1,4-dihydropyridines promote the anti-tuberculosis (Tb) activities of clofazimine

Doi:10.3390/molecules24162873
(2019)
Regiochemical Control in the Diels-Alder Reaction of Substituted Naphthoquinones. The Directing Effects of C-6 Oxygen Substituents

Doi:10.1021/jo00146a034
(1982)
CONVERGENT SOLID PHASE PEPTIDE SYNTHESIS. I. SYNTHESIS OF PROTECTED SEGMENTS ON A HYDROXYMETHYLPHENYLOXYMETHYL RESIN USING THE BASE LABILE FMOC α-AMINE PROTECTION. MODEL SYNTHESIS OF LHRH.

Doi:10.1016/0040-4020(82)85102-8
(1982)
Studies on heterocyclic enaminonitriles. I. Synthesis and aromatization of 2-amino-3-cyano-1-ethoxycarbonyl-4,5-dihydropyrroles

Doi:10.1248/cpb.30.2357
(1982)
Synthesis of Some 2,5-Disubstituted 5-Aryl-4-oxo-4,5-dihydropyrrole Derivatives from 2,5-Disubstituted 3-Ethoxycarbonyl-5-hydroxy-4-oxo-4,5-dihydropyrroles

Doi:10.1055/s-1982-29890
(1982)

Article Doi