Preparation and ring-opening reactions of N-diphenylphosphinyl aziridines

Article abstract of DOI:10.1016/S0040-4020(97)10430-6

Monochiral N-Diphenyphosphinyl aziridines ('N-Dpp azinidines') may efficiently be prepared from monochiral 2-aminoalcohols. Such aziridines undergo ring-opening reaction with a variety of nucleophiles in good yield. Dephosphinylation is accomplished under mild conditions.