New aryl/heteroaryl C-N bond cross-coupling reactions via arylboronic acid/cupric acetate arylation

DOI: 10.1016/S0040-4039(98)00504-8

Source and publish data:

Tetrahedron Letters p. 2941 - 2944 (1998)

Update date:2022-07-29

Topics:

Authors:

Lam, Patrick Y. S.

Clark, Charles G.

Saubern, Simon

Adams, Jessica

Winters, Michael P.

Chan, Dominic M. T.

Combs, Andrew

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Article abstract of DOI:10.1016/S0040-4039(98)00504-8

A new aryl/heteroaryl C-N bond cross-coupling reaction via the arylboronic acid/cupric acetate arylation of N-H containing heteroarenes has been discovered. This new methodology is mild, proceeds at room temperature exposed to air, and works for many heteroarenes and arylboronic acids providing good yields of N-arylated heteroarenes.

Full text of DOI:10.1016/S0040-4039(98)00504-8

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