Tetrahedron Letters p. 2941 - 2944 (1998)
Update date:2022-07-29
Topics:
Lam, Patrick Y. S.
Clark, Charles G.
Saubern, Simon
Adams, Jessica
Winters, Michael P.
Chan, Dominic M. T.
Combs, Andrew
A new aryl/heteroaryl C-N bond cross-coupling reaction via the arylboronic acid/cupric acetate arylation of N-H containing heteroarenes has been discovered. This new methodology is mild, proceeds at room temperature exposed to air, and works for many heteroarenes and arylboronic acids providing good yields of N-arylated heteroarenes.
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