Tetrahedron p. 2953 - 2966 (1998)
Update date:2022-08-03
Topics:
De Lang, Robbert-Jan
Van Hooijdonk, Marcel J.C.M.
Brandsma, Lambert
Kramer, Hester
Seinen, Willem
The aryl-benzyl cross-coupling in the presence of copper-, nickel- and palladium-catalysts has been investigated with a number of chlorine- and methyl-substituted arylmetal compounds ArM (M = MgBr, ZnCl) and (substituted) benzylic halides ArCH2X. The results have been applied in the selective synthesis of some toxicologically interesting tetrachlorobenzyltoluenes.
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