Tetrahedron p. 4375 - 4386 (1998)
Update date:2022-07-30
Topics:
Karupaiyan
Srirajan
Deshmukh
Bhawal
A diastereoselective synthesis of (±) c/s-β-1actams (5 and 6) via cycloaddition reactions of N1-(α-thiophenyl)benzyl imines (3) with acid chlorides (4) in the presence of triethylamine is described. The deprotection of N1-(α-thiophenyl)benzyl group has been achieved by oxidation using potassium persulfate to give N-unsubstituted β-lactams (7) in good yields.
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Doi:10.1021/ja973715j
(1998)Doi:10.1016/S0022-328X(98)00418-5
(1998)Doi:10.1016/S0040-4020(99)00594-3
(1999)Doi:10.1016/0040-4039(96)00299-7
(1996)Doi:10.1039/a801350k
(1998)Doi:10.1007/s10600-013-0504-5
(2013)
