A new convenient synthesis of bifunctional chelating agent 1-(4- aminobenzyl)-1,4,8,11-tetraazacyclotetradecane-N',N'',N'''-triacetic acid [1- (H2NBn-TETA)]

DOI: 10.1016/S0040-4039(98)00372-4

Source and publish data:

Tetrahedron Letters p. 2659 - 2662 (1998)

Update date:2022-09-26

Topics:

Authors:

Maillet Maillet

Kwok Kwok

Noujaim Noujaim

Snieckus

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Article abstract of DOI:10.1016/S0040-4039(98)00372-4

A convenient and short synthesis (3 steps, 50% overall yield) of the bifunctional chelating agent 1-(4-aminobenzyl)-1,4,8,11 - tetraazacyclotetradecane - N'-, N''-, N'''- triacetic acid (4) via a boron- protection strategy is reported.

Full text of DOI:10.1016/S0040-4039(98)00372-4

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Product name:[8,11-Bis-benzyloxycarbonylmethyl-4-(4-nitro-benzyl)-1,4,8,11-tetraaza-cyclotetradec-1-yl]-acetic acid benzyl ester

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