Synthesis of 1,2-aminoalcohols by Ti(IV)-catalyzed photohydroxymethylation of chiral aldimines

DOI: 10.1016/S0040-4039(98)00339-6

Source and publish data:

Tetrahedron Letters p. 2535 - 2536 (1998)

Update date:2022-07-30

Topics:

Authors:

Griesbeck, Axel G.

Buhr, Stefan

Lex, Johann

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Article abstract of DOI:10.1016/S0040-4039(98)00339-6

The N-(α-phenylethyl) alkylated aldimines 3a-c are conveniently hydroxymethylated with moderate diastereoselectivities by means of irradiation in methanolic solution in the presence of titanium(IV)chloride.

Full text of DOI:10.1016/S0040-4039(98)00339-6

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