Regioselective synthesis of 8-hydroxytetrahydroquinolines by the cyclization of m-hydroxyphenethyl ketone O-2,4-dinitrophenyloximes

Article abstract of DOI:10.1246/cl.1998.437

8-Hydroxy-1,2,3,4-tetrahydroquinolines are synthesized from m-hydroxyphenethyl ketone O-2,4-dinitrophenyloximes by the cyclization on the sp² nitrogen atom of the oxime derivatives using sodium hydride and sodium cyanoborohydride.