Regioselective synthesis of 8-hydroxytetrahydroquinolines by the cyclization of m-hydroxyphenethyl ketone O-2,4-dinitrophenyloximes

DOI: 10.1246/cl.1998.437

Source and publish data:

Chemistry Letters p. 437 - 438 (1998)

Update date:2022-08-05

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Authors:

Ono, Ayako

Uchiyama, Katsuya

Hayashi, Yujiro

Narasaka, Koichi

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Article abstract of DOI:10.1246/cl.1998.437

8-Hydroxy-1,2,3,4-tetrahydroquinolines are synthesized from m-hydroxyphenethyl ketone O-2,4-dinitrophenyloximes by the cyclization on the sp² nitrogen atom of the oxime derivatives using sodium hydride and sodium cyanoborohydride.

Full text of DOI:10.1246/cl.1998.437

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