Solid phase synthesis of 2,6-disubstituted-4(3H)-pyrimidinones targeting HIV-1 reverse transcriptase

DOI: 10.1016/S0040-4039(97)84377-8

Source and publish data:

Tetrahedron Letters p. 3307 - 3310 (1998)

Update date:2022-08-02

Topics:

Authors:

Nizi, Emanuela

Botta, Maurizio

Corelli, Federico

Manetti, Fabrizio

Messina, Flavia

Maga, Giovanni

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The solution and solid phase synthesis of 6-substituted 2-[(4- hydroxybutyl)amino]-4(3H)-pyrimidinones 1 as HIV-1 RT inhibitors is described.

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