Bioorganic and Medicinal Chemistry Letters p. 1837 - 1842 (1997)
Update date:2022-08-03
Topics:
Williams, Matthew A.
Lew, Willard
Mendel, Dirk B.
Tai, Chun Y.
Escarpe, Paul A.
Laver, W. Graeme
Stevens, Raymond C.
Kim, Choung U.
The structure-activity relationships (SAR) for a new class of potent inhibitors (1) of influenza neuraminidase are described. Systematic modifications of substituents at the C-3, C-4, and C-5 positions of the carbocyclic ring were performed to establish fundamental SAR to assist in the design of potent inhibitors with activity against both of influenza A and B viruses.
View MoreNanjing Yuance Industry&Trade Co., Ltd.
website:http://www.njyuance.cn/
Contact:+86-25-85439097
Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
website:http://www.easchem.com
Contact:+86-731-89722861 89722891
Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
Contact:86-931-8272767
Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Shijiazhuang Yunxuan Im&Export Co.,Ltd.
Contact:+86-311-83037514
Address:No.6 Hongbin Road
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd
Contact:+86-533-5415882
Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
Doi:10.1002/anie.201903204
(2019)Doi:10.1016/S0040-4039(00)72391-4
(1966)Doi:10.1016/S0020-1693(97)06094-5
(1998)Doi:10.1139/v69-006
(1969)Doi:10.1021/acs.jmedchem.0c00137
(2020)Doi:10.1021/ol0172572
(2002)
