7-(2-Aminomethyl-1-azetidinyl)-4-oxoquinoline-3-carboxylic acids as potent antibacterial agents: Design, synthesis, and antibacterial activity

DOI: 10.1248/cpb.46.787

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 787 - 796 (1998)

Update date:2022-08-03

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Authors:

Fujita, Masahiro

Chiba, Katsumi

Tominaga, Yukio

Hino, Katsuhiko

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Article abstract of DOI:10.1248/cpb.46.787

2-Aminomethyl-1-azetidinyl, -1-pyrrolidinyl, and -1-piperidinyl groups were designed as novel C-7 substituents for potential antibacterial quinolone agents. Of the three substituents, the 2-aminomethyl-1-azetidinyl group (compound 12a) was found to be the

Full text of DOI:10.1248/cpb.46.787

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