7-(2-Aminomethyl-1-azetidinyl)-4-oxoquinoline-3-carboxylic acids as potent antibacterial agents: Design, synthesis, and antibacterial activity

DOI: 10.1248/cpb.46.787

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 787 - 796 (1998)

Update date:2022-08-03

Topics:

Authors:

Fujita, Masahiro

Chiba, Katsumi

Tominaga, Yukio

Hino, Katsuhiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.787

2-Aminomethyl-1-azetidinyl, -1-pyrrolidinyl, and -1-piperidinyl groups were designed as novel C-7 substituents for potential antibacterial quinolone agents. Of the three substituents, the 2-aminomethyl-1-azetidinyl group (compound 12a) was found to be the

Full text of DOI:10.1248/cpb.46.787

NII-Electronic Library Service

Products guided by the article

Product name:(S)-C-(1-Benzyl-azetidin-2-yl)-methylamine

Cas No:209607-03-4

R&D Labs maybe for 209607-03-4

Beijing Century Richap Chemistry Co.,Ltd

Contact:+86- 010-64455497

Address:Guannan County, Lianyungang City, Jiangsu Province, China
Suzhou Time-chem Technologies Co., Ltd.

Contact:0512-63983931/68086856

Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
Sinochem Jiangsu Co.,Ltd.

Contact:86-25-51817806

Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china
SHIFANG SUHONG CHEMICAL CO.,LTD

Contact:+86-838-2224563

Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China
Hunan Zhongqi Pharmaceutical Co., Ltd

website:http://www.hnzqzy.com

Contact:0730-8722288 13807308622

Address:Wanjiafan Road ,Yueyang Economic And Technological Development Zone ,Hunan,PRC

Relevant to this article

Doi:10.1021/ja01334a062
(1933)
Advances in 2H-Azaphosphirene complex chemistry

Doi:10.1080/10426509708545614
(1997)
CuI/Oxalic Diamide Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amines

Doi:10.1021/jacs.5b08411
(2015)
Stereochemical studies on the synthesis of 1,2,3,4- tetrahydroisoquinolin-4-ols

Doi:10.1016/S0957-4166(98)00164-5
(1998)
New tetrahydronaphthalene derivatives as combined thromboxane receptor antagonists and thromboxane synthase inhibitors

Doi:10.1016/S0960-894X(98)00221-2
(1998)
(E)-1-(Phenylsulfonyl)-4-(trimethylsilyl)-1-butene: An Advantageous Synthetic Equivalent for the 1-(1,3-Butadienyl) Anion and the 1,1-(1,3-Butadienyl) Dianion

Doi:10.1021/jo970546c
(1998)

Article Doi