2'-O-propargyl oligoribonucleotides: Synthesis and hybridisation

DOI: 10.1016/S0040-4020(98)00271-3

Source and publish data:

Tetrahedron p. 5899 - 5914 (1998)

Update date:2022-07-30

Topics:

Authors:

Grotli, Morten

Douglas, Mark

Eritja, Ramon

Sproat, Brian S.

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Article abstract of DOI:10.1016/S0040-4020(98)00271-3

Fully modified oligonucleotide sequences containing 2'-O- propargylribonucleotides were synthesised on automated DNA-synthesisers using the phosphoramidite approach. A highly selective alkylation procedure was used to introduce the propargyl functionality

Full text of DOI:10.1016/S0040-4020(98)00271-3

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