Tetrahedron p. 6739 - 6750 (1998)
Update date:2022-08-04
Topics:
Gesson, Jean-Pierre
Renoux, Brigitte
Tranoy, Isabelle
In connection with the synthesis of cytotoxic annonaceous acetogenin analogs, enantiomerically pure threo (and erythro)-trans THF synthons have been prepared from D-glucose. These synthons are characterized by the presence of two methoxy (or hydroxy) groups in the THF ring, each in a cis configuration with respect to the vicinal side chain.
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