Novel D-ring analogues of podophyllotoxin as potent anti-cancer agents

DOI: 10.1016/S0960-894X(98)00232-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1391 - 1396 (1998)

Update date:2022-08-05

Topics:

Authors:

Subrahmanyam, Duvvuri

Renuka Renuka

Rao, C.V. Laxmana

Sagar, P. Sangeeta

Deevi, Dhanvanthri S.

Babu, J. Moses

Vyas Vyas

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Article abstract of DOI:10.1016/S0960-894X(98)00232-7

Several D-ring modified analogues of podophyllotoxin were prepared viz semi-synthesis starting from naturally occuring podophyllotoxin and determined their in vitro anti-cancer activity. Most of the analogues have shown good activity towards human cancer cell lines.

Full text of DOI:10.1016/S0960-894X(98)00232-7

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