Novel D-ring analogues of podophyllotoxin as potent anti-cancer agents

DOI: 10.1016/S0960-894X(98)00232-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1391 - 1396 (1998)

Update date:2022-08-05

Topics:

Authors:

Subrahmanyam, Duvvuri

Renuka Renuka

Rao, C.V. Laxmana

Sagar, P. Sangeeta

Deevi, Dhanvanthri S.

Babu, J. Moses

Vyas Vyas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00232-7

Several D-ring modified analogues of podophyllotoxin were prepared viz semi-synthesis starting from naturally occuring podophyllotoxin and determined their in vitro anti-cancer activity. Most of the analogues have shown good activity towards human cancer cell lines.

Full text of DOI:10.1016/S0960-894X(98)00232-7

Products guided by the article

Product name:(5R,6R,7R)-methyl 7-(hydroxymethyl)-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylate

Cas No:211043-39-9

R&D Labs maybe for 211043-39-9

He Bei Shun Er Chemical Co., LTD.

Contact:86-0311-86996932/86860168

Address:No 18,North street
lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Xuzhou Tianrun Chemical Co.,Ltd

website:http://www.tianrunchem.cn

Contact:86-516-83832636

Address:fuxing road
Shifang Taifeng New Flame Retardant Co., Ltd

Contact:02884721008

Address:tingjiang industrial park, hefeng town
Shandong Xingshun New Material Co., Ltd.

website:http://www.sd-xingshun.com

Contact:+86-519-86461196

Address:Middle of Luhua East Road, Dingtao District

Relevant to this article

Heterocycles LXXVIII. Electrophilic substitution of 2′-phenyl-4R-2,4′-bisthiazoles

Doi:10.1007/pl00013474
(1998)
Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP)

Doi:10.1016/S0968-0896(98)00029-7
(1998)
Mechanism of the Reaction of Nitriles with Alkaline Hydrogen Peroxide. Reactivity of Peroxycarboximidic Acid and Application to Superoxide Ion Reaction

Doi:10.1246/bcsj.54.793
(1981)
Coumarin 1,4-dihydropyridine derivatives

Doi:10.1016/S0968-0896(98)00037-6
(1998)
cis- and trans-2-(isocyanomethyl)-5,5-dimethyl-2-oxo-4-phenyl-1,3,2-dioxaphosphorinane - Synthesis and structure of the first chiral isocyanomethylphosphonate synthons

Doi:10.1002/(SICI)1099-0690(199808)1998:8<1511::AID-EJOC1511>3.0.CO;2-G
(1998)
Conformationally constrained substance P analogues: The total synthesis of a constrained peptidomimetic for the Phe⁷-Phe⁸ region

Doi:10.1021/jo991649t
(2000)

Article Doi