Pd-catalyzed cyclization reactions of acetylene-containing α-amino acids

Article abstract of DOI:10.1016/S0040-4039(98)00910-1

Acetylene-containing amino acids, obtained in enantiopure form via an enzymatic resolution process, serve as versatile intermediates in the synthesis of various highly functionalized heterocycles. The key transformations, intramolecular OC- and NC-bond formation, proceed via Pd- catalysis.