Tetrahedron Letters p. 4971 - 4974 (1998)
Update date:2022-08-04
Topics:
Dankwardt, Sharon M.
Dankwardt, John W.
Schlessinger, Richard H.
A vinylogous urethane approach is utilized to synthesize the C1-C8 fragment of okadaic acid. The key steps include an asymmetric alkylation, a hydroxyl directed iodocarbonate cyclization and a stereoselective cyanohydrin formation.
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Doi:10.1021/np980031w
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(1998)
