Tetrahedron p. 11567 - 11580 (1998)
Update date:2022-08-05
Topics:
Hiscock, Steven D.
Hitchcock, Peter B.
Parsons, Philip J.
A new approach to the synthesis of Prelog-Djerassi Lactonic acid (1) is reported. A key step in this synthesis involves an Ireland-Claisen rearrangement/silicon-mediated fragmentation sequence to provide the carbon framework in (1).
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