A concise enantio- and diastereo-controlled synthesis of (-)-quinic acid and (-)-shikimic acid

Article abstract of DOI:10.1039/a805775c

(-)-Quinic acid and (-)-shikimic acid, both recognized as the key intermediates in the shikimate pathway in plants and microorganisms, have been synthesized concisely in an enantio- and diastereo-controlled manner starting from a synthetic equivalent of (R)-4-hydroxycyclohex-2-enone.