49. Synthesis of tenuilobine, a bis-polyamine alkaloid from Oncinotis tenuiloba, and its transamidation to isotenuilobine

Article abstract of DOI:10.1002/hlca.19960790221

From the leaves of Oncinotis tenuiloba STAPF, a novel polyamine alkaloid, tenuilobine (9), was isolated. This paper presents the synthesis of 9, as well as the base-catalyzed Zip reaction of 9, leading to the transamidation product isotenuilobine (10). Th