Bioorganic and Medicinal Chemistry Letters p. 2447 - 2450 (1998)
Update date:2022-08-03
Topics:
Ma, Dawei
Ma, Zhaochun
Kozikowski, Alan P.
Pshenichkin, Sergey
Wroblewski, Jarda T.
Two analogues 2, 3 of (S)-α-methyl-3-carboxylphenylalanine 1 were synthesized to test their activity for metabotropic glutamate receptors (mGluRs). Both compounds 2 and 3 were inactive as antagonist for mGluRs, but 2 showed weak agonistic activity for GluR6 in contrast to that reported by Kemp and co-workers.
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Doi:10.1016/0039-128X(83)90100-9
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(2014)Doi:10.3987/COM-98-8231
(1998)
