Tetrahedron Letters p. 8213 - 8216 (1998)
Update date:2022-08-03
Topics: Synthesis Amino acids Efficient Synthesis Substituted oxopiperazines
Mohamed, Nazim
Bhatt, Ulhas
Just, George
The synthesis of substituted oxopiperazines, which may act as conformationally constrained peptide mimics, is reported. The synthesis is based on the cyclization of sulfonamide dipeptides with dibromoethane as the 1,2-dielectrophile. Alternatively, these
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