A short and facile synthetic route to prenylated flavones. Cyclodehydrogenation of prenylated 2'-hydroxychalcones by a hypervalent iodine reagent

Article abstract of DOI:10.1016/S0040-4020(98)00853-9

The first synthesis of the prenylated flavones kanzonol-D (1), -E (3) and yinyanghuo-C (4) was accomplished by cyclodehydrogenation of the appropriately substituted 2'-hydroxychalcones 16, 14 and 11, respectively, in presence of phenyl-iodine(III) diaceta