Chiral zirconium-catalyzed asymmetric mannich-type reactions using acylhydrazones as imine equivalents

Article abstract of DOI:10.1246/cl.1998.1131

In the presence of a catalytic amount of a new zirconium catalyst, prepared from zirconium(IV) t-butoxide and (R)-3,3′-dibromo-1, 1′-bi-2-naphthol, 4-trifluoromethylbenzoyl-hydrazones reacted with silyl enolates to afford the corresponding adducts, β-N′-a