Synthesis and quantitative structure-activity relationships of N-(3- oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidines as Na/H exchange inhibitors

DOI: 10.1248/cpb.46.1716

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1716 - 1723 (1998)

Update date:2022-07-29

Topics:

Authors:

Yamamoto, Takeshi

Hori, Manabu

Watanabe, Ikuo

Tsutsui, Hisayoshi

Harada, Kengo

Ikeda, Shqji

Maruo, Joji

Morita, Tominori

Ohtaka, Hiroshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1716

N-(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidines 4 were prepared and tested for Na/H exchange inhibitory activities in order to clarify the structure-activity relationship (SAR). Quantitative SAR (QSAR) analysis of 6-carbonylguanidines 4 in

Full text of DOI:10.1248/cpb.46.1716

NII-Electronic Library Service

Products guided by the article

Product name:8-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carboxylic acid methyl ester

Cas No:219477-37-9

R&D Labs maybe for 219477-37-9

Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Shenzhen Hongyuan Import & Export Co., Ltd.

Contact:0755-26407171

Address:Shenzhen Hongyuan Chemical New Materials Technology Co., Ltd.
shanghai meicheng chemical co .,ltd(expird)

Contact:+86-21-50677091

Address:Room 302, Building 7, No.1000, Jinhai Road

Relevant to this article

Doi:10.1021/jo00831a025
(1970)
Enhanced diastereoselectivity in the asymmetric Ugi reaction using a new 'convertible' isonitrile

Doi:10.1021/jo982186e
(1999)
Doi:10.1021/jo01264a021
(1969)
Application of Baylis-Hillman methodology in a novel synthesis of quinoline derivatives

Doi:10.1039/a807827k
(1998)
Multisubstituted urea derivatives of hydrazines by a flexible approach with potential application in combinatorial chemistry

Doi:10.1055/s-1998-2217
(1998)
Synthesis of novel analogues of the calicheamicin γ₁ and esperamicin A_1B oligosaccharides

Doi:10.1039/b006113l
(2001)

Article Doi