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Synthesis and quantitative structure-activity relationships of N-(3- oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidines as Na/H exchange inhibitors

DOI: 10.1248/cpb.46.1716

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1716 - 1723 (1998)

Update date:2022-07-29

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Authors:

Yamamoto, TakeshiYamamoto, Takeshi

Hori, ManabuHori, Manabu

Watanabe, IkuoWatanabe, Ikuo

Tsutsui, HisayoshiTsutsui, Hisayoshi

Harada, KengoHarada, Kengo

Ikeda, ShqjiIkeda, Shqji

Maruo, JojiMaruo, Joji

Morita, TominoriMorita, Tominori

Ohtaka, HiroshiOhtaka, Hiroshi

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Article abstract of DOI:10.1248/cpb.46.1716

N-(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidines 4 were prepared and tested for Na/H exchange inhibitory activities in order to clarify the structure-activity relationship (SAR). Quantitative SAR (QSAR) analysis of 6-carbonylguanidines 4 in

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Full text of DOI:10.1248/cpb.46.1716

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Products guided by the article

Product name:8-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carboxylic acid methyl ester

Cas No:219477-37-9

219477-37-9

R&D Labs maybe for 219477-37-9

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